Before you make your Sweet 16 March Madness predictions
Let’s get the basics in place first. The Sweet 16 is the third proper round of the NCAA Division 1 college basketball tournament. It features sixteen teams who will each have made it through the first and second rounds of the eliminator games.
The 2025 March Madness has its Sweet 16 games played on March 23 and 24. These will be split up into West, East, Midwest and South Regional games that are held in Las Vegas, New York, Kansas City and Louisville.
It’s a part of the tournament where we start to get a good idea of those teams who have the form to go all of the way and win March Madness. However, when you’re making your NCAA basketball Sweet 16 picks, you are just betting on which teams reach this stage of the knockout tournament.
What goes into our March Madness Sweet Sixteen picks
All of our college basketball picks are based on so much more than just gut instinct. We use all of our combined experience to know which basketball statistics to power our picks, plus we know what kinds of locker-room rumors to pay attention to and what gossip to ignore. But on the whole, our basketball picks will always be powered by the following ingredients:
- Past form:
Houston Cougars have won their last nine games and this means that they are probably more likely to win their next game.
- Head to heads:
Those local rivalries like Arizona Wildcats against Arizona State Sun Devils can put past form out of the window. That recent 88-89 win for the Sun Devils is just an example of this and should guide your bets accordingly.
- Key players:
Stars like Oscar Tshiebwe of Kentucky are more than capable of powering lesser teams to bigger things. As a result, our picks will always take account of these basketball stars of the future.
- Coaching experience:
Any college basketball team with an experienced coach is in with a strong chance of making the Sweet 16. We’ll let you know who those legendary coaches are who are powering their teams to glory.
The favorites in our March Madness Sweet Sixteen predictions
So who are the 16 teams who will make it through to this stage of March Madness 2025? We believe that the following teams have the form and experience required to make the Sweet Sixteen:
- Houston Cougars:
With a playing record of 27-2, Houston are at the top of the NCAA rankings and deservedly so.
- Alabama Crimson Tide:
While the controversy over Brandon Miller may have clouded things, we think that we’ll be seeing Alabama in the Sweet 16.
- Kansas Jayhawks:
Last year’s March Madness winners Kansas Jayhawks are looking good again to succeed in the NCAA Division I tournament.
- UCLA Bruins:
No team has won March Madness as much as UCLA. Could they make it their 12th title in 2025?
- Purdue Boilermakers:
Purdue are fifth place in the NCAA rankings thanks to their impressive 24-5 playing record.
- Arizona Wildcats:
We think that the Wildcats will put that agonizing defeat against Arizona State behind them and power their way to the Sweet Sixteen.
- Baylor Bears:
The Bears may have struggled with inconsistency, but their 22-8 record shows that they can get big wins when it counts.
- Tennessee Volunteers:
While Tennessee can be hard to predict, we’re fairly certain that the Volunteers will make the Sweet 16.
- Texas Longhorns:
At ninth place in the NCAA rankings are Texas Longhorns who have a good chance of making the last sixteen.
- Gonzaga Bulldogs:
Any team with a player like Drew Timme in their ranks are going to be worth a look and we think that Gonzaga could go far.
- Connecticut:
Connecticut have been up and down this year, but their 22-7 record shows that they are in with a good chance of making the Sweet 16.
- Indiana Hoosiers:
While Indiana have struggled with away from, they can work wonders with the crowd behind them.
- Xavier Musketeers:
With a playing record of 21-8, Xavier should go far, although they might not progress beyond the Sweet 16 round.
- TCU Horned Frogs:
While the Horned Frogs have lost 10 games, they have enough attacking strength to make it through to the later rounds.
- Virginia Cavaliers:
Most people would agree that the Cavaliers are one of the better teams in the NCAA and their 22-6 record is a testament to this belief.
- Creighton Bluejays:
Creighton might be inconsistent but we think that they could be one of the surprise packages of this year’s March Madness.
Outsiders featuring in the Sweet 16 predictions for March Madness
Of course, every March Madness throws up a few surprises. From rank underdogs breaking through to the later rounds to surefire favorites falling by the wayside, it all helps to make this tournament compelling viewing. So here are just some of those teams who could shake up the Sweet 16 in 2025:
- Marquette Golden Eagles:
Five wins in a row means that things are looking good at Marquette.
- Saint Marys Gaels:
With a 25-6 record, the Gaels are impossible to ignore.
- Kentucky Wildcats:
At 20-4 and with four wins in a row, we think that Kentucky could be coming good at just the right time.
- Kansas State Wildcats:
With a 22-7 playing record, the Wildcats could be worth a look for your Sweet 16 bets.
Advice for making your own college basketball Sweet 16 predictions
While we’re pretty sure about our picks, we realize that everyone will have their own opinions about what’s going to happen in March Madness 2025. So be sure to follow these tips before you make your own Sweet 16 predictions:
Just check the NCAA rankings and you’ll get a fair idea about who is most likely to make the Sweet 16.
Few people would have guessed that Saint Peter’s would go far in the 2022 March Madness, so do your research and see who will be this year’s tournament.
Check the tournament schedule
Analyze who is playing who in the first and second rounds to see who has the easiest route to the Sweet 16.
Some teams definitely rely on star players, so note the team sheets to see if any injuries could ruin a certain team’s chances of success.
Conclusion - Your home for reliable March Madness Sweet 16 picks
Each game played in 2025 March Madness will obviously have an effect on what happens in the later rounds. This means that what happens in the First Four, First Round and Second Round will affect your NCAA basketball Sweet 16 predictions.
Naturally, we’ll be keeping this resource updated with all of the latest action from March Madness so that you can make your predictions based on all of the relevant facts and statistics.
Plus we’ll be sure to keep our college basketball Sweet 16 picks updated so that you get a good idea of who’s most likely to reach this round. So check back here so that you can make your NCAA March Madness Sweet 16 predictions with confidence.
March Madness Sweet 16 predictions FAQ
❓ What does the NCAA Sweet 16 bracket mean?
Check out our guide that shows you exactly what the Sweet 16 bracket means and we’ll even give you our March Madness Sweet 16 picks. Don’t forget that you can even take it up a level by checking out our
March Madness Final 4 predictions
too.
💪 What are some good NCAA Sweet 16 picks?
We’ve got all of the March Madness Sweet 16 predictions you need right here. Plus we can help you out with some
March Madness survivor pool picks
so that you get expert betting advice for every stage of the NCAA Division I tournament.
🔮 How should I make Sweet 16 predictions?
Take a look at our guide to see how you should be making your March Madness Sweet 16 predictions. After all, you’ll need a lot more than just gut instinct.
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