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Sweet 16 Betting Lines: Updated Guide Betting on The NCAA Sweet Sixteen

Last Updated on Apr 28, 2025
Fact checked by: Ronnie Flores

It’s so easy to enjoy March Madness Sweet 16 gambling online. Read our guide to see how you can bet on this thrilling round of the NCAA Division I championship.

We’ve selected our picks for the 2023 Sweet 16 and have even got a great selection of sportsbooks who can be counted on to give you the best March Madness odds and promos. So all you need to do is check out this guide and see how you can legally and safely enjoy some March Madness Sweet Sixteen gambling.

Top sportsbooks that offer the best March Madness Sweet 16 odds and promos

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Caesars
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Virginia (US) Lottery Board
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All about March Madness Sweet 16 gambling

The Sweet 16 is a round in the March Madness college basketball tournament and it frequently offers up the most unpredictable action.

This is because the Sweet 16 follows on from the First Round and Second Round which means that most of the rank outsiders will have been removed while there’ll still be a few underdogs ready to cause a big upset.

As a result, lots of people will love to bet on the Sweet 16 which is where our guide comes in. This means knowing how to bet on which teams will actually reach the Sweet 16 and understanding who has the best chance of winning the single eliminator game to go through to the Elite Eight.

The 2023 March Madness has its Sweet 16 games on March 23 and 24, and these take place at arenas in Las Vegas, New York, Kansas City and Louisville.

Before you rush to put down your Sweet 16 bets, it’s important to check whether you are actually legally allowed to gamble in your state. This is because all states have their own sports betting laws that may or may not allow you to bet real money on sporting events, and things get even more complex when it comes to college sports like March Madness.

This is why it’s a good idea to only use the sportsbooks featured in the banners on our site. After all, each of these sportsbooks has been checked to make sure that they are licensed in the US, and they’ll also give you nothing but fair and competitive odds for each of the Sweet 16 games. Just remember that you’ll always have to be at least 21 years old to play at these sports betting platforms.

State Sweet 16 Gambling Laws
New Jersey Sweet 16 Gambling is allowed, but not on teams from the state or games taking place in the state.
New York You cannot wager on any Sweet 16 teams involving a New York-based team.
Pennsylvania You can gamble on Sweet 16
Michigan You can gamble on Sweet 16
Maryland You can gamble on Sweet 16
Colorado You can gamble on Sweet 16, but prop bets are prohibited.
Arizona You can gamble on Sweet 16, but prop bets are not permitted.
Kansas You can gamble on Sweet 16
Indiana You can gamble on Sweet 16
West Virginia You can gamble on Sweet 16

How to bet on Sweet 16

The good news is that if your state has legalized online sports betting it’s very simple to bet on any Sweet 16 game. Here is a step-by-step guide for what you need to do:

  1. Pick a sportsbook: You can pick pretty much any sportsbook featured on our site and find that they’ll give you great odds for each round of March Madness.
  2. Create a customer account: This usually just requires you to fill in a registration form with your personal details and then you’ll be expected to verify this information by providing some form of photo ID.
  3. Make your deposits: You can usually do this by making payments via Visa, Mastercard, PayPal, Discover or ACH bank transfer.
  4. Get your sign up offer: Most first sportsbook deposits will trigger some kind of welcome offer, just don’t forget that you may be required to enter in a promo code.
  5. Place your bets: Now you can browse the March Madness odds to find the Sweet 16 bets. Click on the odds that you want to bet on, type in how much you want to bet into the betting slip and submit your bet.

 

Simple tips for betting on Sweet 16

It’s never easy betting on a major event like Sweet 16 where there is so much emotion and so many variables. However, we think that the following tips should stop you from making too many mistakes with your Sweet 16 bets.

Set a budget

After all, anything can happen in a Sweet 16 and so it’s best to set a budget so that you can cover any unexpected losses. 

Follow a team’s form

Any team on a good winning streak will have the confidence to go far, but you should remember that overconfidence can be any team’s undoing. 

Don’t rely on rankings

The NCAA rankings give you a good guide to roughly how well each team is doing, but you shouldn’t follow these rankings too blindly. Instead, think about how each competing teams’ strengths and weaknesses may play against each other. 

Note the star players

Certain players like Drew Timme have the power to dramatically change their team’s fortunes, but watch out for any unexpected injuries to these college basketball stars. 

Try different betting lines

While it’s fine to bet on the money line, you might get better value by betting on things like totals, player props or even try some in-play betting. 

Conclusion - Your home for March Madness Sweet Sixteen online gambling

Betting on the Sweet 16 is a lot of fun and our guide has given you everything you need to bet on confidence on this tricky round of March Madness. After all, you can simply sign up to one of our recommended sportsbooks, use our Sweet 16 picks and then have a strong chance of getting something back from your bets.

However, we should note that the odds and predictions for these Sweet 16 games will be changing in the run-up to the round. So make sure that you bookmark this page to get the best predictions for this fascinating round of March Madness.

March Madness Sweet 16 gambling online FAQ

👀Where can I find March Madness bets today?

Take a look at our guide to see how you can enjoy March Madness Sweet 16 gambling online today. Plus we can reveal all you need to know about March Madness Elite 8 gambling for later in the tournament.

💪Who’s leading in the March Madness finals odds?

Read our guide to March Madness Sweet Sixteen gambling to see which teams have the best chance of making it through to the finals. Perfect for knowing which NCAA basketball futures odds to bet on.

❓How does March Madness championship betting work?

Check out our guide to March Madness Sweet Sixteen gambling to see how you can bet on this epic college basketball championship. Don’t forget that we can also help you find some legal and safe March Madness betting apps to download. 

🏅Which sportsbook has the best March Madness betting odds?

Don’t miss our guide to March Madness Sweet 16 gambling online where you’ll get some solid recommendations for which sportsbooks to use. Essential for making sure that you get the best college basketball moneyline odds for this thrilling round.

🏀What is the NCAA Sweet 16?

Take a look at our guide to March Madness Sweet Sixteen gambling to see what this round is. Plus we can even show you how the over under odds for NCAA basketball can help you find greater value when betting on the Sweet Sixteen games.

Our Team
Sara Jane Gamelli
Sara Jane Gamelli
Writer | Bettor
Sadonna Price
Sadonna Price
Editor | Writer
Kenny Ducey
Kenny Ducey
Sports Reporter | Capper
Ronnie Flores
Ronnie Flores
Editor | Senior Writer
David Astramskas (Redapples)
David Astramskas (Redapples)
Editor | Senior Writer
Top Betting Sites
Top Betting Bonuses
Bet365
4.9/5
BetMGM
4.6/5
FanDuel
4.5/5
Caesars
4.5/5
DraftKings
DraftKings
DraftKings Review
4.4/5
Bet365
Bet365 Promo
Get $150 in Bonus Bets Win or Lose when you bet $5!
T&Cs apply
4.9/5
Subject to meeting qualifying criteria. Minimum wager $5. Minimum odds -500 or greater. $10 minimum deposit. Paid in Bonus Bets. Bonus Bets wager excluded from returns. New customers only. Available in app only. Max. prize, game restrictions, time limits and T&Cs apply. Deposit required. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply.Gambling Problem? Call 1-800-Gambler 21+
BetMGM
BetMGM Promo
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T&Cs apply
4.6/5
FanDuel
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T&Cs apply
4.5/5
Caesars
Caesars Promo
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4.5/5
DraftKings
DraftKings Promo
New Customers Bet $5, Get $300 in Bonus Bets If Your Bet Wins!
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4.4/5
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