Eagles vs Giants Anytime Touchdown Scorer Predictions: NFL Best Bets for Thursday, October 9

Thursday Night Football (TNF) is back, and there's an NFC East division rival matchup between the Eagles and Giants!

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Today, Jalen Hurts and the Philadelphia Eagles (4-1, 2-0 away) will face Jaxson Dart and the New York Giants (1-4, 1-1 home).

7-3 against the Giants over the last 10 outings, the Eagles are coming off a 21-17 loss against Bo Nix and the Denver Broncos. Four-point favorites, it was the Broncos who erased a 14-point deficit to come back for the victory. Even so, the Eagles are 4-1 on the season, and remain the heavy favorite to win the NFC East (-220).

The Giants have officially entered the Jaxson Dart era, and his NFL debut was spoiled with a 26-14 loss against Spencer Rattler and the New Orleans Saints. While the Giants have a strong defensive line with Dexter Lawrence, Brian Burns, Kayvon Thibodeaux, and Abdul Carter, the Giants gave up four field goals and two touchdowns to Rashid Shaheed and Jordan Howden (fumble recovery).

Both teams are heading in opposite directions, as New York continues its rebuild under a demanding schedule. The reigning Super Bowl Champions, the Eagles, have the second-best odds behind the Buffalo Bills to win the 2025-2026 Super Bowl (+700). The Giants, meanwhile, have the fifth-highest odds to hold up the Lombardi Trophy (+400000).

NFC East Matchup: Philadelphia Eagles vs New York Giants

Although the Giants will host the Eagles at MetLife Stadium tonight, they are massive +310 moneyline and 7.5-point spread underdogs. This season, Philadelphia is 3-2 ATS, while New York is 2-3 ATS.

With star receiver Malik Nabers out for the remainder of the 2025-2026 NFL season with an ACL tear, the Giants average just 17.4 points per game. They now have an Eagles squad that regressed somewhat offensively, but still managed to put up 25 points per game.

If you're betting on the NFL, Thursday's matchup featuring the Philadelphia Eagles and New York Giants will kick off at 8:15 p.m. ET on Prime Video. According to the weather forecast, winds are predicted at 8.9 mph at the start of the game.

As far as injuries, Eagles offensive lineman Landon Dickerson is out for today's matchup, while Edge Rusher Jalen Carter is questionable. For New York, Right Tackle Jermaine Eleuemunor is questionable, and Wide Receiver Darius Slayton is ruled out.

Featuring Saquon Barkley against his former team, let's dive into my best bets and anytime touchdowns scorer predictions for Thursday, October 9, NFL Week 6 matchup featuring the Eagles and Giants.

All of my bets in this article were made separately within FanDuel Sportsbook.

NFL Week 6 Best Bets: Eagles vs Giants Anytime Touchdown Scorer Predictions for Thursday, October 9

Saquon Barkley Anytime TD Odds: -165 (FanDuel)

2025-2026 NFL Stats

GP: 5 | Carries: 83 | Rush Yards: 267 | Rush Avg.: 3.2 | Rush TD: 3 | Rush long: 17 |REC: 17 | Targets: 19 | Receiving Yards: 128 | Rec Avg.: 7.5 | Receiving TD: 1 | Receiving long: 47

My first best bet for Thursday, I placed one unit on Philadelphia Eagles star running back Saquon Barkley to score a touchdown (-165) against the New York Giants.

I know the odds are a bit juiced here, but you can find value at -165 odds. Plus, Barkley gets to face his former team, the Giants.

From a rushing perspective, Barkley's efficiency is down, averaging just 3.2 yards per carry. However, he's rushed for 128 yards and three touchdowns through five weeks. A receiving threat in the backfield, Barkley has 128 receiving yards and one touchdown.

Given that frustration has been mounting for Eagles receivers A.J. Brown and DeVonta Smith, Philadelphia has mainly relied on its running game. While Jalen Hurts leads the team with three rushing yards, here's why I'll take Barkley.

Saquon Barkley Faces His Former Team, The New York Giants

Having scored four touchdowns on the season, Barkley has crossed the plain in all but one game (against the Chargers). Recording just one touchdown in his lone game against his former team, Barkley has another prime matchup.

This season, the Giants give up the seventh most touchdowns to running backs, as we've seen with Omarion Hampton (Chargers), Javonte Williams (Cowboys), Kareem Hunt (Chiefs), and Miles Sanders (Cowboys). RB1 or RB2, it doesn't matter.

Aside from the projected strength of the Giants' defensive line, New York has given up the sixth most rushing yards this season (700), and allows 140 yards on the ground per game. While Barkley's longest rush of the season is 17 yards, is this the game he breaks loose? Either way, he's also a threat in the backfield.

Final NFL Anytime Touchdown Eagles vs Giants Betting Prediction: Saquon Barkley ATS Odds: -165 (FanDuel)

Overall, I like Hurts and Barkley, and there's a high chance they both score a touchdown tonight. However, the Giants rank No. 30 in rush EPA, and New York ranks dead last in the NFL in defensive rushing DVOA. On the offensive end, the Eagles sit No. 10 in rushing DVOA.

• I love the matchup here. I'm taking Saquon Barkley to score a touchdown against his former team, the New York Giants. 

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DeVonta Smith Anytime TD Odds: +240 (FanDuel)

2025-2026 NFL Stats

GP: 5  | Receptions: 25 | Targets: 30 | Receiving Yards: 272 | Avg: 10.9| Rec TD: 1 | Rush TD: 0 | Long Rec: 52 | First Down: 11

My second-best bet for today, I placed one unit on Philadelphia Eagles wide receiver DeVonta Smith to score a touchdown (+240) against the New York Giants.

While this is a gamble, I love the odds at +240. If there was a meeting held between Jalen Hurts and the receivers, this could be a breakout game for Smith.

Notably, the Eagles have been a run-heavy team, although they do run 59.6 percent of their plays under head coach Nick Sirianni.

Smith has just one lone touchdown on the season, which came on September 21 against the Los Angeles Rams. Technically considered a WR2 next to A.J. Brown, he leads all receivers in receptions (25) and receiving yards (272).

Why DeVonta Smith Can Score A Touchdown Today

Although tight end Dallas Goedert has been Hurt's clear favorite red zone target with four touchdowns, it's been Smith who's been targeted the most inside the 20 ahead of Brown and Jahan Dotson.

This season, Smith has been targeted 50 percent in the red zone and has 18 receiving yards on four targets inside the 20. Not to mention, he led all receivers, playing 98 percent of snaps in week 5 against the Broncos.

This is a prime matchup for Smith, who's been a Giants killer in the end zone. Over the last seven games against New York since 2021, he's scored a touchdown in four of them. Now he gets a Giants squad that allows the ninth-most touchdowns to wide receivers.

An elite slot and wide receiver, he's coming off a massive 114 receiving yard performance against Denver. With that, he had eight receptions and 10 targets. Over the last three games, he's been targeted 21 times with 18 receptions.

Final NFL Anytime Touchdown Eagles vs Giants Betting Prediction: DeVonta Smith ATS Odds: +240 (FanDuel)

WR2s have had success against the Giants this season, as we've seen Tyquan Thornton (Chiefs) score a touchdown against New York. Bettors also witnessed Rashid Shaheed, Quentin Johnston, and Deebo Samuel score touchdowns against the New York team.

Overall, the Giants rank No. 17 in defensive passing DVOA, and Smith is putting up a 23.3 percent target share. Plus, he has an 83.3 percent catch rate.

• I'm taking DeVonta Smith to score a touchdown Thursday night. He has four red zone looks over the last three games. 

Cam Skattebo Anytime TD Odds: +155 (FanDuel)

2025-2026 NFL Stats

GP: 5 | Carries: 63 | Rush Yards: 240 | Rush Avg: 3.8 | Rush TD: 2 | Rush long: 24 |REC: 18 | Targets: 22 | Receiving Yards: 143 | Rec Avg.: 7.9 | Receiving TD: 0 | Receiving long: 21

My third best bet for today, I placed one unit on New York Giants rookie running back Cam Skattebo to score a touchdown against the Eagles.

While back, Tyron Tracy Jr. is set to return this week, Skattebo has emerged as the Giants' leading receiver. With two touchdowns against the Cowboys and Chiefs, he hasn't crossed the plane in two weeks. However, he's rushed for 59+ yards in three consecutive weeks, including 79 yards on 25 carries in week 4 against the Chargers.

It's difficult to predict how Tracy's return will impact Skattebo, but we do know a few things. Skattebo played 75 and 68 percent of snaps over the last two weeks. With that said, Tracy hasn't attempted a single rush inside the 20.

Skattebo leads Devin Singletary by a mile with 31 red zone rushing attempts and two touchdowns on 16 attempts. If we know one thing, Skattebo is the red zone guy for head coach Brian Daboll.

This season, the Eagles allow the 24th most rushing touchdowns to running backs, and have allowed backs to score a touchdown in three straight weeks. That includes J.K. Dobbins (Broncos), Bucky Irving (Buccaneers), and Kyren Williams (Rams). Plus, Cowboys running back Javonte Williams scored two touchdowns against the Eagles on September 4.

Final NFL Anytime Touchdown Eagles vs Giants Betting Prediction: Cam Skattebo ATS Odds: +155 (FanDuel)

While the Eagles rank No. 14 in defensive DOVA, they are decent against the pass. Where it differs is the run game, where they rank No. 21 in rushing DVOA. Plus, Philadelphia ranks No.1 3 in rush EPA.

• While Skattebo will have more competition tonight, he's averaged 16.7 carries over the last three weeks and 315 yards. I'm taking Cam Skattebo to score a touchdown tonight. With a 3.2 percent rushing touchdown rate, I'm confident he will cross the plain today.