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NFL Best Bets Week 11: 3 Best NFL Picks & Predictions For Sunday, November 16

Publish Date: Nov 16, 2025
Fact checked by: Ronnie Flores
Key Points
  • SJ breaks down her three best bets for the Sunday, November 16 NFL matchups!

NFL week 11 is finally here, and there are 13 games to bet on!

Josh Allen Buffalo Bills NFL MNF

(Photo by Cooper Neill/Getty Images)

There's an early morning matchup in Madrid featuring the Commanders and Dolphins!  This week, there are several highly anticipated matchups ahead that include rivalries among several divisions!

The Tennessee Titans will face a CJ Stroud-less Houston Texans. 2-0 against the Titans since last season, the books have Houston as 5.5-point spread favorites on the road. Next up, we have top quarterbacks in Baker Mayfield and Josh Allen.  Set to take place in Orchard Park, the Buffalo Bills will host the Tampa Bay Buccaneers.

A matchup, the Los Angeles Rams will host Seattle Seahawks at SoFi Stadium. Both tied at 7-2, it's a battle for first place! The Rams are three point favorites today. A matchup in the AFC, Patrick Mahomes and the Kansas Chiefs will face Box Nix and the Denver Broncos. Chasing Denver for first place in the division, the Chiefs are 4.5-point favorites.

The comeback team, Lamar Jackson and the Baltimore Ravens, will face division rival Cleveland Browns on the road.  The Ravens last defeated the Browns 41-17, and are 2-0 against Cleveland since last season. The night game will feature the two of the top teams in the NFC in the Detroit Lions and Philadelphia Eagles.

Here are my three best bets, player prop picks, and predictions for the Sunday, Week 11 NFL November 16 matchups! Ballislife has the current FanDuel odds for all 13 NFL matchups!

Week 11 Best Bets #1: Josh Jacobs

  • OVER 79.5 Rushing Yards (-114 Fanatics)

My first best bet for today, I placed one unit on Green Bay Packers running back Josh Jacobs to record over 79.5 rushing yards against the New York Giants.

The Packers' offense does worry me, as it's been quite abysmal over the last two weeks. Fresh off a two-game losing streak, they've dropped games against the Philadelphia Eagles and Carolina Panthers. Through the losses, they've scored just 20 combined points.

Sunday is a chance for the Packers to come alive, especially against a 2-6 Giants team that just fired head coach Brian Daboll.  Plus, there are several injuries to the Giants' defense. Rakeem Nunez-Roches is doubtful to play, along with Tyler Nubin and Kayvon Thibodeaux. Now, Paulson Adebo and Bobby Okereke are questionable!

This puts Jacobs in a prime spot, given New York's recent struggles and injuries. While the Giants are supposed to have one of the best defensive lines in football, that hasn't been the case this year.  Overall, they rank No. 28 in defensive DVOA and No. 32 in defensive rush DVOA.

Now in his second season with Green Bay, Jacobs is having a decent year with 608 rushing yards and 11 touchdowns. Developing a decent connection with quarterback Jordan Love, he's totaled 237 receiving yards in the backfield.

Final NFL Week 11 Best Bet & Prediction: Josh Jacobs OVER 79.5 Rushing Yards (-114 Fanatics)

Coming off 74 rushing yards, Jacobs has scored a touchdown in six straight games and has 38 carries alone over the last two games.  Now he faces a Giants team that allows the second-most rushing yards to running backs. Moreover, we recently saw Christiaan McCaffrey (106 yards) and Saquon Barkley (150) torch the Giants on the ground.

I'm taking Josh Jacobs to record over 79.5 rushing yards. The Giants have allowed 417 rushing yards over the last four weeks to RB1s, and New York ranks dead last in the NFL in rush EPA.

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 Week 11 Best Bets #2: Tee Higgins

  • OVER 55.5 Receiving Yards (-125 Fanatics)

My second best bet for today, I placed one unit on Cincinnati Bengals Tee Higgins to record over 55.5 receiving yards today.

Higgins has established quite a connection with quarterback Joe Flacco and is coming off a 121-yard performance against the Bears. With that, he's coming off a season high of seven receptions and nine targets.

He has a prime matchup today against a Steelers defense that allows the most receiving yards to receivers. Knowing the Bengals, their defense is atrocious, and the Steelers have proven themselves vulnerable.

Overall, Tee Higgins has been a Steelers killer, soaring over this player prop line in five of the last seven head-to-head matchups against the Steelers. In fact, he's averaged north of 92 receiving yards in the last seven games against Pittsburgh.

Final NFL Week 11 Best Bet & Prediction: Tee Higgins OVER 55.5 Rushing Yards (-125 Fanatics)

While Pittsburgh has been decent against WR2, they've given up 115 yards to Michael Pittman, 161 to Ja'Marr Chase, and 126 yards to Justin Jefferson. Of all NFL teams, the Steelers allow the most receiving yards per game (194.1)

I'm taking Tee Higgins to record over 55.5 receiving yards today. I think the books are sleeping on the line, especially since he recorded 96 against the Steelers on October 16.

Week 11 Best Bets #3: Cincinnati Bengals

  • +5.5 (-110 Fanatics)

My third-best bet for Sunday, I placed one unit on the Cincinnati Bengals to cover the 5.5-point spread against the Pittsburgh Steelers.

I'm expecting a high-scoring game, as the Bengals rank last in defensive DVOA and the Steelers rank 13th. With that, it's a division rival game, and 5.5 points is a good number for a Steelers team coming off a 25-10 loss to the Indianapolis Colts.

Not only did the Bengals defeat the Steelers 33-31 on October 16, but they are 6-4 against Pittsburgh in their last 10 head-to-head matchups. Who would have thought that 40-year-old Joe Flacco would face 41-year-old Aaron Rodgers, who would highlight this event, but here we are!

The Bengals are 2-0 against the Steelers since last season and have a 3-6-1 ATS record so far through 10 games. However, Each of their last four meetings has been decided by six points or less.

I'm taking the Bengals to cover the 5.5-point spread as underdogs. The Bengals have just one victory over the last seven games, but the Steelers are 1-3 in their last four games. If anything, the Bengals have proven they can hang defensively under Joe Flacco. They are coming off a 42-point loss against the Bears and are averaging 37.6 points over the last three weeks.

Final NFL Week 11 Best Bet & Prediction: Cincinnati Bengals +5.5 (-110 Fanatics)

The Bengals have more losses than wins; however, each of their last losses has been decided by five points or less. Even over the last three games, two of them have been decided by two points or less. I'm laying the points with the Bengals on Sunday.

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