NFL: Jacksonville Jaguars vs San Francisco 49ers Odds, Predictions & Betting Tips for 11/12/2023

Jacksonville Jaguars – San Francisco 49ers

Tip:

Jags

-145.0

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Home Win 1

0.7%

145

Draw X

0%

Away Win 2

0%

-160

The Jacksonville Jaguars travel to the San Francisco 49ers in a mouthwatering Week 10 encounter. Both sides top their respective divisions, but whilst the Jags are on a five game winning run, the Niners have stumbled in recent weeks and will be desperate to get back on track. 

To help you enjoy the game, our NFL betting experts have put together their exclusive matchday tip. So read on to discover their thoughts on this huge matchup.

We’ve only just reached the halfway point of the regular season, but already the Jacksonville Jaguars look certain to make the playoffs. After a mediocre start to the campaign, they have put together a run of five successive victories that has left them clear of the pack in the AFC South.

With the likes of Trevor Lawrence and Travis Etienne in excellent form on offense, plus a defense that has made big plays all season, the Jags look like one of the AFC’s strongest teams. If they can win on Sunday against one of the NFC’s best, it will raise hopes of a Super Bowl appearance even further.

Despite being top of the NFC West, these are troubling times for the 49ers. QB Brock Purdy is experiencing the first dropoff in his NFL career, the previously impenetrable defense is giving up some big plays and the Niners’ injury list is growing by the week.

Whilst most sports picks and predictions before the season made the Niners favorites to make the Super Bowl, those expectations have dipped slightly. However, this is still a squad packed with elite talent and a win against one of the AFC’s finest will get their season back on track.

Head to Head

The two teams have met 6 times previously, with the Jaguars holding two wins and the Niners four. San Francisco have won the last four matchups between the teams, most recently a 30-10 victory in 2021. The last time the Jags beat the Niners was back in 2005.

Tip:

Jags

Best Odd

-145

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Before looking at the NFL Betting Apps for the latest odds on this game, make sure you read our key statistical highlights. These stats look at key gameday details that will put you in the perfect place to make accurate NFL Picks.

The 49ers are marginal favorites for the game and can be backed at -160 for the win. The Jaguars are available at +145 to win on the road.

This looks like the game of the weekend. Some of the best players in the league will be on show, so expect fireworks and a very close contest. That being said, we think the Jags will have enough quality and confidence to secure a huge road win. They are playing some inspired football at the moment, whilst the Niners are going through a tough patch.

In a game that is likely to come down to fine margins, the likes of Etienne and Lawrence will be crucial in getting the Jags over the line.